Optimising treatment for advanced RCC
Optimising treatment for advanced RCC
Journey through an interactive patient case
Journey through an interactive patient case
Prof. Viktor Grünwald
In this interactive patient case video, you'll meet a 62-year-old man with advanced renal cell carcinoma (RCC) and follow his journey through selection of first- and second-line therapies and managing associated toxicities. Along the way, you'll answer questions at key points, and engage with clickable resources to deepen your understanding of:
- The different efficacy and safety profiles of targeted and immunotherapy treatments for RCC
- How to implement targeted therapies and immunotherapies into treatment strategies for advanced RCC
- Optimal sequencing of treatments
- The cause of toxicities and strategies to improve tolerability and manage side effects whilst maintaining optimal efficacy
Prof. Viktor Grünwald
Medical Oncologist
Universaity Hospital Essen
Germany
Viktor Grünwald is a professor for Interdisciplinary Urooncology at the University Hospital Essen. Professor Grünwald specialises in Internal Medicine and Medical Oncology. His main areas of research interest are in renal cell carcinoma, soft tissue sarcomas, head and neck cancers, with an emphasis on the development of molecular and immunotherapies. Prof Grünwald graduated from the Medical School Hannover in 1998, after which he was appointed as a Private Lecturer in Haematology and Oncology at the same institution. He became professor for Haematology and Oncology at the Medical School Hannover in 2014. Professor Grünwald was appointed to the steering committee for genitourinary (GU) cancers (non-prostate) at the ESMO and ESMO ASIA Congress and is part of scientific committees of the International Kidney Cancer Symposium (EIKCS), German Cancer Congress (DKK) and the German Society for Hematology and Oncology (DGHO). He has co-chaired the Phase 3 Working Group of the Central European Society of Anticancer Drug Research (CESAR) studies group and a former member of the board of the German Medical Oncology studies group (AIO). Prof. Grünwald chairs the AIO Head and Neck (SCCHN) Working Group and within the AIO he is the former spokesman of the Sarcoma (STS) Working Group. Within the German Cancer Society, he chairs the Working Group for renal tumors (RCC) and is co-chair of the interdisciplinary head and neck tumors group. He chairs the ESMO preceptorship on SCCHN and is part of the faculty of the ECCO-AACR-EORTC-ESMO workshop on methods in clinical cancer research. His current trial proposals explore novel concepts in RCC, STS and SCCHN, focusing on translational research and drug development of immunotherapies in these indications.
Prof. Viktor Grünwald has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:
- Alexion
- Amgen
- Aspivix
- Astellas
- AstraZeneca
- Bayer
Diagnosis and treatment of TRK fusion-positive GI cancers
Interactive patient case | 11 min | Jun 2023
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This programme was made for you: your opinion matters
Share your feedback in just 4 clicks and help us to continue to create the content you need.
I agree that this educational programme:
Was valuable to me:
1/4
Has improved my knowledge of this topic:
2/4
Is likely to change my clinical practice:
3/4
Was balanced and unbiased:
4/4
Clinical Takeaways
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Current clinical practice for patients with advanced ccRCC is frontline combination of immunotherapy-VEGFR TKI for IDMC intermediate/poor-risk patients
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Adverse events can generally be managed through dosing strategies, enabling the patient to remain on first-line therapy as long as possible
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Switching to 2nd line therapy should ideally be at the point of disease progression
This educational programme is supported by an Independent Medical Education Grant from Eisai Europe Limited.
GU CONNECT is an initiative of COR2ED, supported by an Independent Educational Grant from AstraZeneca, Bayer and Eisai Europe Limited.