Understand the MoA of PARP inhibitors and targeting DNA Damage Response (DDR)
Understand the MoA of PARP inhibitors and targeting DNA Damage Response (DDR)
Dr. Robert L. Coleman, Prof. Simon Boulton
A short video explaining the concept of DDR, the role of Homologous Recombination Repair (HRR) in DNA repair and the impact of BRCA1 and BRCA2 mutations. It explores PARP inhibitors as the proof of concept for targeting DDR, demonstrating how they work and their clinical benefit.
Dr. Robert L. Coleman
Gynaecologic Oncologist
US Oncology Research
United States (US)
Prof. Simon Boulton
Senior Scientist
Francis Crick Institute
United Kingdom (UK)
Video | 
5 min
|
Sep 2021
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Prof. Simon Boulton
Senior Scientist
Francis Crick Institute
United Kingdom (UK)
